⚠️ FOR RESEARCH PURPOSES ONLY — This compound is not FDA approved. All data presented is from clinical trials for educational reference.
Popular Peptides
TRZ
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Compound Information
Technical specifications
What Is TRZ?
Stability Information
About TRZ
Tirzepatide is a high-purity lyophilized peptide researched for its unique ability to act as a dual agonist for both the Glucose-dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like Peptide-1 (GLP-1) receptors. Originally designed to investigate synergistic metabolic pathways, it has become a primary subject of study in fat metabolism and weight management research. This TRZ-2 product provides a consistent and stable reagent for academic and industrial research into molecular signaling, peptide behavior, and tissue remodeling. It is intended strictly for laboratory and research development purposes only.
Mechanism of Action
The mechanism involves the simultaneous activation of GIP and GLP-1 receptors. Activation of the GLP-1 receptor slows gastric emptying and reduces food intake signaling in the brain, while GIP receptor activation is studied for its role in improving insulin sensitivity and regulating lipid metabolism in adipose tissue. Together, these dual pathways investigate a more comprehensive approach to glucose homeostasis and energy expenditure than single-receptor agonists.
What Research Has Shown
Dual Incretin Signaling & Homeostasis
Findings from GIP and GLP-1 receptor activation studies
Research Highlights
Product Specifications
- Molecular Formula
- C225H348N48O68
- Molecular Weight
- 4813.45g/mol
- Sequence
- Tyr-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Leu-Asp-Lys-Ile-Ala-Gln-Lys-Ala-Phe-Val-Gln-Trp-Leu-Met-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser
- Purity
- ≥99% (HPLC verified)
- Form
- Lyophilized powder
- Appearance
- White to off-white powder
- Solubility
- Soluble in water, bacteriostatic water
- Storage
- -20°C (lyophilized), 2-8°C (reconstituted)
Research Studies
Frequently Asked Questions
It is a first-in-class "twincretin," meaning it targets both the Glucose-dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like Peptide-1 (GLP-1) receptors.
No, it is intended strictly for in-vitro and approved in-vivo animal research by qualified professionals and not for human or veterinary medical use.
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