⚠️ FOR RESEARCH PURPOSES ONLY — This compound is not FDA approved. All data presented is from clinical trials for educational reference.
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SLU-PP-332 Capsules
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Compound Information
Technical specifications
What Is SLU-PP-332 Capsules?
Stability Information
About SLU-PP-332 Capsules
SLU-PP-332 is a first-in-class synthetic agonist of the Estrogen-Related Receptors (ERRs), specifically targeting the $\alpha$, $\beta$, and $\gamma$ isoforms. These receptors are key regulators of the metabolic genes typically activated during aerobic exercise. In research settings, SLU-PP-332 is used to investigate how pharmacological activation of the ERR pathway can enhance oxidative metabolism and fatty acid oxidation in skeletal muscle. These 500mcg capsules provide a consistent reagent for studying mitochondrial biogenesis and energy expenditure in laboratory models. As an “exercise mimetic,” it allows researchers to explore metabolic homeostasis and endurance signaling pathways without physical exertion in experimental subjects.
Mechanism of Action
The mechanism involves SLU-PP-332 binding to the Estrogen-Related Receptors (ERR$\alpha/\beta/\gamma$), which are orphan nuclear receptors. Once activated, these receptors increase the expression of genes involved in mitochondrial function and oxidative phosphorylation. This leads to an increase in the cell’s ability to burn fat for energy and enhances the overall metabolic capacity of muscle tissue, effectively mimicking the biological effects of endurance training in research assays.
What Research Has Shown
Skeletal Muscle Homeostasis
Findings from ERR signaling investigations
Research Highlights
Product Specifications
- Molecular Formula
- C22H14F3NO3S
- Molecular Weight
- 429.4g/mol
- Sequence
- N/A
- Purity
- ≥99% (HPLC verified)
- Form
- Lyophilized powder
- Appearance
- White to off-white powder
- Solubility
- Soluble in water, bacteriostatic water
- Storage
- -20°C (lyophilized), 2-8°C (reconstituted)
Research Studies
Frequently Asked Questions
It refers to compounds that trigger the same metabolic pathways and gene expressions that usually occur during physical exercise.
It acts as a potent agonist for the Estrogen-Related Receptors (ERR$\alpha$, ERR$\beta$, and ERR$\gamma$).