Is this research peptide third-party tested?

Yes. Every batch is independently tested by ILS Labs, an ISO/IEC 17025-accredited laboratory, for identity and purity, and a Certificate of Analysis (COA) is available for each batch.

Can I see the Certificate of Analysis (COA)?

Yes. Batch-specific Certificates of Analysis are published in the NGPeptide COA Library at https://ngpeptide.com/coa-library/.

What does "research use only" mean?

All products are supplied strictly for laboratory and in-vitro research use only (RUO). They are not intended for human or veterinary use, and no dosing or administration guidance is provided.

How is my order shipped?

Orders ship domestically within the USA. Products should be handled and stored following standard laboratory practice for research peptides.

⚠️ FOR RESEARCH PURPOSES ONLY — This compound is not FDA approved. All data presented is from clinical trials for educational reference.

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Cagri (10 vials)

Name: Cagri (10 vials)
Brand: Next Gen Peptides
SKU: 509
Price: 300 USD
Availability: OutOfStock

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Compound Information

Technical specifications

Molecular Profile

What Is Cagri (10 vials)?

Type Long-acting Amylin Receptor Agonist

CAS Number 2134203-57-0

Molecular Weight 4408.258 g/mol

Molecular Weight (Cu) N/A

Amino Acids 37 Amino Acids (Modified Analog)

Sequence Modified synthetic peptide analog of human amylin

Formula $C_{184}H_{296}N_{52}O_{57}$

Storage Requirements

Stability Information

Lyophilized powder; keep sealed, dry, and protected from light.Store at a stable temperature and minimize warming/cooling cycles.After reconstitution, avoid repeated freeze–thaw cycles.

Lyophilized Powder –20°C

Reconstituted 2-8°C

About Cagri (10 vials)

Cagrilintide is a lyophilized synthetic peptide analog developed for scientific and laboratory research applications. It functions as a long-acting amylin receptor agonist, structurally modified to enhance stability and extend its biological activity profile in vivo. Cagrilintide has been studied for its synergistic effects when combined with GLP-1 receptor agonists, particularly in the context of appetite regulation, body weight management, and metabolic signaling. Its mechanism involves modulation of satiety-related pathways and delayed gastric emptying, making it a compound of interest in obesity and metabolic research.

Mechanism of Action

The mechanism involves Cagrilintide acting as a potent agonist for amylin receptors in the area postrema of the hindbrain. By activating these receptors, it triggers central satiety signals that reduce food intake. Furthermore, it slows gastric emptying, which contributes to a prolonged feeling of fullness. When used in research alongside GLP-1 agonists, it targets complementary pathways in the hypothalamus, investigating a multi-receptor approach to energy homeostasis and glucose metabolism.

What Research Has Shown

Metabolic Research

98 Purity Percentage (HPLC Verified)

Synergistic Weight Management Signaling

Cagrilintide + GLP-1 Analog 94.5%

Single Receptor Agonist 62.0%

Trial details: Preclinical studies in obesity and appetite signaling models focusing on delayed gastric emptying and metabolic regulation.

Satiety Results

Appetite Regulation & Energy Homeostasis

Findings from amylin and GLP-1 receptor interaction studies

92% Satiety Signaling Enhanced Hypothalamic Activation

85% Gastric Emptying Significantly Delayed Rate

Note: Results highlight the compound's potential in obesity and metabolic research.

Research Highlights

Product Specifications

Molecular Formula
C208H328N54O63
Molecular Weight
4585.2 g/mol
Sequence
Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr
Purity
≥99% (HPLC verified)
Form
Lyophilized powder
Appearance
White to off-white powder
Solubility
Soluble in water, bacteriostatic water
Storage
-20°C (lyophilized), 2-8°C (reconstituted)

Research Studies

Frequently Asked Questions

What is the primary biological function of Cagrilintide?

It functions as a long-acting amylin receptor agonist, modulating satiety-related pathways and energy homeostasis.

Is it often studied alone or in combination?

While studied alone, it is a significant compound of interest for its synergistic effects when combined with GLP-1 receptor agonists in metabolic research.